If you like fantasy but want a game that pokes fun at the genre (maybe you've played Munchkin)...
Red Dragon Inn —
Designed by Cliff Bohm, Geoff Bottone, Cold FuZion Studios and Colleen Skadl, published by Slugfest Games with outstanding artwork by Kennon James, Doug Kovacs, Rhonda Libbey and Beth Trott.
For 2 to 4 players (best with 4) ages 13 and up (or older). Plays in about 45 minutes.
The theme includes characters like wizards, warriors, thieves, elves, trolls, and such - but they've just come home from adventuring and simply want to get drunk and maybe do some gambling. Each character in this card game is a parody of the traditional characters, trying to drink each other under the table. Can you be the last one standing at the end of the night? Cards with words might slow things down a little for the first few plays while you learn the game, but once you become familiar with the characters, the game move fast, and you may find yourself doing a bit of play-acting even if you don't normally like that kind of thing.
(Several expasions are available enabling play by up to 10 at once with many additional characters and play enhancements.)